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Human Immunology Biosciences (HI-Bio) is a US-based precision immunology company leveraging human genetics to deliver patient-targeted approaches to autoimmune disorders. HI-Bio is a new company that Monograph is co-incubating with Arch Venture Partners. Monograph co-led the Series A financing round in August 2021.

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AviadoBio is a UK-based gene therapy company with a program to treat an inherited form of frontotemporal dementia using pioneering novel routes of administration. Monograph co-led the Series A financing round with NEA in November 2021.

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Ascend is a UK-based gene and cell therapy contract development and manufacturing organisation with differentiated offering in adeno-associated virus technologies to meet an underserved European market. Ascend is a Monograph build with partner Tim Funnell as interim CEO. Monograph seeded Ascend in December 2021.

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Exited August 2022

Gilead Sciences to Acquire MiroBio for approx $405 million

MiroBio is a therapeutics company developing checkpoint agonist antibodies, a new class of therapies designed to restore immune balance and treat autoimmune disease. This work is based on 15 years of research from the University of Oxford. Monograph participated in the Series B financing round in June 2022.

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RegASK is a Singapore based global regulatory technology SaaS company enabling businesses in the biopharma, consumer health, medtech and food industries to leverage AI to strengthen and scale their regulatory and compliance capabilities. Monograph led the Series A financing in December 2022.

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Maxion Therapeutics is a Cambridge, UK based company developing antibody drugs against ion channels and G-protein-coupled receptors (GPCRs) using proprietary KnotBody® platform to overcome challenges with this target class. Series A funding round was led by LifeArc Ventures, including Monograph Capital and BGF as equal participants.

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